PT / INR | Determination of Blood Coagulation Indicators

Prothrombin Time (PT) Test by Quick is a globally recognized screening test for coagulation, designed for assessing the extrinsic and common coagulation pathways (consisting of factors VII, X, V, II, and fibrinogen). The PT test is used for monitoring patients taking oral anticoagulants, determining coagulopathies before surgical interventions, or diagnosing congenital and acquired factor deficiencies.

This test is also a diagnostic tool for diagnosing disseminated intravascular coagulation syndrome (DIC), assessing liver function or vitamin K deficiency, which may occur due to severe nutritional disorders or vitamin K metabolism disorders, as factors II, VII, and X are dependent on vitamin K. Test Principle The test contains thromboplastin and calcium, which activate the extrinsic coagulation cascade when added to citrated human plasma. The time interval from adding the reagent to fibrin clot formation is measured and indicated in seconds.

Recommendations:

• It is recommended to perform prophylactically once a year, before surgeries, for disease diagnosis, and treatment control periodically as directed by a physician.
• The test results are influenced by age, medication use, diet, smoking, pregnancy.
• For test sampling, it is necessary to arrive fasting for 12-14 hours and abstain from aspirin and other anticoagulants for 2-3 days.