Anti-CCP | Antibodies against cyclic citrullinated peptide

Antibodies against cyclic citrullinated peptide (Anti-CCP) are one of the most sensitive and specific laboratory markers for the diagnosis of rheumatoid arthritis. These antibodies can be detected in the body before clear clinical symptoms appear, allowing the test to identify the disease early and start treatment. Anti-CCP helps to differentiate rheumatoid arthritis from other forms of arthritis, such as osteoarthritis or infectious arthritis.

The value of the indicator is closely related to the course of the disease - the higher the concentration of Anti-CCP, the more likely an aggressive form of the disease and faster joint destruction. This test is often combined with the rheumatoid factor (RF) test to confirm the diagnosis and assess the severity of the disease.

Test principle: Anti-CCP antibodies are determined by an immunochemical method from a venous blood sample. Results are presented in units/ml. Test interpretation should be performed in conjunction with clinical symptoms and other laboratory markers.

Recommendations:

• Recommended for patients experiencing persistent joint pain or swelling.
• Useful for confirming the diagnosis of rheumatoid arthritis or determining the form of the disease.
• Performed to assess disease activity, progression, and treatment efficacy.
• Recommended for patients with a positive family history or signs of other autoimmune diseases.
• The test is recommended to be performed after fasting for at least 12 hours.