Anti-IA2 (antibodies against tyrosine phosphatase)

Anti-IA2 (anti-tyrosine phosphatase antibodies) is a protein similar to tyrosine phosphatase that is found in pancreatic β-cells as dense granules. These antibodies are more often found at a younger age, i.e. i.e. in children under 5 years of age, and they are associated with rapid progression of diabetes mellitus. Anti-IA2 is found in 55-60%. newly diagnosed type I CD persons and less than 3 percent. healthy individuals.