Pharmacogenetic Drug Tolerance Test (17 Genes)

Pharmacogenetic Drug Selection Test

The innovative pharmacogenetic test helps assess how a patient's genetic traits can influence drug absorption, metabolism, efficacy, and potential adverse effects. The test results are presented in a clear, clinically applicable report that assists the doctor in making more personalized decisions regarding treatment strategy, drug selection, or dosage.

Safer Treatment Begins with Genetic Information

The same medication can work differently for different people. For one patient, the standard dose might be appropriate, while for another, it might be too weak, too strong, or may cause undesirable reactions. These differences are determined by genes responsible for drug breakdown, transport, and the body's response to treatment.

The pharmacogenetic test helps to pre-evaluate how a patient's body may react to certain medications. This allows for more precise treatment planning, reducing the likelihood of trial and error, aiming for better drug efficacy and greater safety.

What Does the Pharmacogenetic Test Indicate?

The test analyzes the patient's genetic data related to drug metabolism and treatment response - conducting an analysis of 17 genes. Based on this information, a personalized report is prepared, providing insights practically applicable to the doctor.

The test report includes:

• The patient's genetic profile related to drug metabolism;
• Genotypes and predicted phenotypes based on them;
• Drug groups and active substances for which genetic traits may be significant;
• Possible warnings regarding drug efficacy or adverse effects;
• Recommendations regarding drug selection or dosage adjustments;
• Clear clinical interpretation prepared according to international pharmacogenetics guidelines.
• Personalized report for the doctor and patient

The results of the pharmacogenetic test are presented in a clearly structured report, convenient for clinical practice. It translates genetic information into specific, treatment-relevant insights, from drug metabolism traits to possible dosage recommendations.

The report helps the doctor quickly assess which drugs might be most suitable for the patient, which medications should be avoided, or in which cases dosage adjustment may be necessary. Information can be grouped by medical fields, making it convenient to apply results in different treatment situations.

When Is It Worth Conducting This Test?

• When taking multiple different medications

The test can be especially useful for patients undergoing multiple drug treatments. In such cases, it is important to evaluate not only the effect of individual drugs but also how genetic traits might influence overall treatment safety.

• When medications do not work as expected

If the prescribed treatment is not effective enough or it takes a long time to find the right medication, pharmacogenetic information can help explain why the body's response to treatment differs from usual and what treatment should be chosen.

• Experiencing undesirable effects

When drugs cause significant side effects, the test can help assess if genetically determined slower or faster drug metabolism influences it.

• Planning long-term treatment

Pharmacogenetic information is relevant for chronic diseases where medications may need to be taken for a long time. Knowing the patient's genetic traits in advance allows forming a more responsible and targeted treatment plan.

• When precise drug dosing is important

For some medications, the appropriate dose is crucial for safety and efficacy. Genetic information can help the doctor assess whether the standard dosage is suitable for the patient.

How Is the Test Conducted?

The patient's sample is taken from a cheek swab. In the laboratory, genetic data are extracted from the sample, which are then analyzed and interpreted. The results are presented in a detailed report.

What Are the Benefits of the Pharmacogenetic Test?

• Helps to personalize treatment
• The test provides additional information that allows the doctor to select more appropriate medications for the patient based on their genetic profile.
• Reduces risk of adverse effects
• Knowing how the patient's body can metabolize certain drugs allows for more responsible evaluation of potential side reactions and their risk.
• Shortens the path to proper treatment
• Instead of long trials and adjustments, the doctor receives additional genetic information that can help make informed decisions more quickly.
• Helps to more accurately adjust doses
• When genetic traits indicate altered drug metabolism, the doctor can evaluate whether dose adjustment or an alternative treatment choice is necessary.

The results of the pharmacogenetic test do not replace a doctor's consultation and are not intended for independent modification of prescribed treatment. Medication use, dosage, or treatment plan can only be changed after consulting a doctor, considering the entire patient's health status, medications used, and clinical situation.

The test is conducted by taking a cheek swab sample

Execution time: 3-5 weeks.