PTH | Parathormone

Parathormone (PTH) – is a hormone produced in the parathyroid glands, responsible for regulating calcium and phosphate metabolism in the body. PTH works together with vitamin D and calcitonin to mobilize calcium and phosphates from bone tissue, increase calcium resorption in the intestine, and promote phosphate excretion through the kidneys. This mechanism ensures a stable level of calcium in the blood, even under changing external conditions.

The amount of parathormone in the body increases in cases of parathyroid adenomas, carcinomas, chronic kidney damage, or vitamin D deficiency. Decreased PTH concentration is most often found in hypercalcemia, vitamin D overdose (intoxication), or autoimmune diseases such as Graves' disease.

Principle of the test: Parathormone concentration is determined by an immunochemical method from venous blood. Results are presented in pg/ml or pmol/l units. When assessing calcium and phosphorus metabolism, the test is often performed together with total calcium, free calcium, phosphorus, and vitamin D tests.

Recommendations:

• Recommended when calcium metabolism disorders are suspected.
• Useful in differentiating the causes of hypercalcemia or hypocalcemia.
• Prescribed for patients with chronic kidney failure or at risk of osteoporosis.
• Performed to monitor the effectiveness of treatment with vitamin D preparations or calcium supplements.
• It is recommended to come for the test fasting for at least 12 hours.