Pharmacogenetic Drug Efficacy Test (22 Genes) with Geneticist's Commentary

Pharmacogenetic Drug Selection Test

Innovative pharmacogenetic testing helps evaluate how a patient's genetic characteristics can influence drug absorption, metabolism, efficacy, and potential adverse effects. The test results are presented in a clear, clinically applicable report that assists the doctor in making more individualized decisions regarding treatment tactics, drug selection, or dosing.

Safer Treatment Begins with Genetic Information

The same drug can affect different people differently. For one patient, a standard dose may be appropriate, while for another it might be too weak, too strong, or could cause adverse reactions. These differences are determined by genes responsible for drug breakdown, transport, and the body's response to treatment.

Pharmacogenetic testing helps evaluate in advance how a patient's body might react to certain drugs. This allows for more precise treatment planning, reducing trial and error, aiming for better drug efficacy and greater safety.

What Does the Pharmacogenetic Test Show?

During the test, the patient's genetic data related to drug metabolism and response to treatment is analyzed - a 17-gene analysis is performed. Based on this information, a personalized report is prepared, providing practically applicable insights for the doctor.

The test report provides:

• The patient's genetic profile related to drug metabolism;
• Genotypes and phenotypes predicted based on them;
• Drug classes and active substances for which genetic characteristics may be significant;
• Possible warnings regarding drug efficacy or adverse effects;
• Recommendations for drug selection or dose adjustment;
• Clear clinical interpretation prepared according to international pharmacogenetics guidelines.
• A personalized report for the doctor and patient

Pharmacogenetic test results are presented in a clearly structured report that is convenient for clinical practice. In it, genetic information is transformed into concrete, treatment-relevant insights - from drug metabolism characteristics to possible dosing recommendations.

The report helps the doctor quickly assess which drugs may be most suitable for the patient, which preparations should be avoided, or in which cases dose adjustment may be necessary. Information can be grouped by medical areas, making it convenient to apply results in different treatment situations.

When Is It Worth Conducting This Test?

• When using multiple different drugs

The test can be especially beneficial for patients undergoing treatment with multiple drugs. In such cases, it's important to evaluate not only the effect of individual drugs but also how genetic characteristics might impact overall treatment safety.

• When drugs do not work as expected

If the prescribed treatment is not sufficiently effective or if a long search is required to find the right drug, pharmacogenetic information can help explain why the body's response to treatment differs from the usual and what treatment should be chosen.

• Experiencing adverse effects

When drugs cause significant side effects, the test can help evaluate whether genetically determined slower or faster drug metabolism is influencing this.

• Planning long-term treatment

Pharmacogenetic information is relevant for chronic illnesses, where drugs may need to be taken for a long time. Knowing the patient's genetic characteristics in advance allows for a more responsible and targeted treatment plan.

• When precise drug dosing is important

For some drugs, the appropriate dose is extremely important for safety and efficacy. Genetic information can help the doctor evaluate whether the standard dosing is suitable for the patient.

How Is the Test Conducted?

A sample is taken from the patient's cheek mucosa swab. In the laboratory, genetic data is obtained from the sample, which is then analyzed and interpreted. Results are presented in a detailed report.

What Are the Benefits of the Pharmacogenetic Test?

• Helps to individualize treatment
• The test provides additional information that allows the doctor to select more suitable drugs for the patient based on his genetic profile.
• Reduces the risk of adverse effects
• Knowing how the patient's body can metabolize certain drugs allows for a more responsible assessment of possible side reactions and their risk.
• Shortens the path to appropriate treatment
• Instead of lengthy trials and corrections, the doctor receives additional genetic information, which can help make informed decisions more quickly.
• Helps adjust doses more precisely
• When genetic characteristics indicate altered drug metabolism, the doctor can evaluate whether dose adjustment or an alternative treatment choice is needed.

Pharmacogenetic test results do not replace a doctor's consultation and are not intended for independently changing the prescribed treatment. Drug use, dosing, or treatment plan can only be changed after consulting with a doctor, evaluating the patient's overall health, medications used, and clinical situation.

The test is performed by taking a sample from cheek scrapes

Completion time: 3-5 weeks.